TRAIL/APO-2L及其受体是TNF家族中的新成员.该系统以其独特的凋亡诱导方式参与抗病毒免疫,免疫赦免以及肿瘤细胞的免疫逃逸等生理作用.TRAIL能诱导多种脑肿瘤细胞系发生凋亡而对神经细胞没有毒性,这为恶性脑肿瘤的治疗提供了新的途径.
- 作 者：
- 吴惺袁先厚袁忠惠
- 作者单位：
- 武汉大学中南医院神经外科,430071
- 刊 名：
- 国外医学（神经病学神经外科学分册）
- 英文刊名：
- FOREIGN MEDICAL SCIENCES SECTION ON NEUROLOGY & NEUROSURGERY
- 年，卷(期)：
- 200128(4)
- 分类号：
- R73
- 关键词：
- TRAIL/APO-2L受体凋亡脑肿瘤
- 机标分类号：
- R28 S7
- 机标关键词：
- 受体系统肿瘤细胞系恶性脑肿瘤诱导方式生理作用神经细胞免疫逃逸免疫赦免凋亡病毒免疫治疗家族毒性
- 基金项目：
- DOI：
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