肿瘤差异表达基因,tumor associated gene
1)tumor associated gene肿瘤差异表达基因
英文短句/例句
1.In silico identification of cancer genes by high throughput analyses生物信息学方法大规模筛选肿瘤差异表达基因
2.Screening of the Genes Highly Expressed in Tumors by mRNA Fluorescent Differencial Display;mRNA荧光差异显示筛选肿瘤中高表达的基因
3.Analysis of Differential Expression Genes in Tumor Tissues of H_(22) Mice with Deficiency of Qi,Yin and Yang中晚期气阴阳虚证H_(22)荷瘤小鼠肿瘤组织差异表达基因的分析
4.Investigating Differential Expression of AGR2 Gene in Barrett"s Esophagus and Its Biological Functions and Mechanism in Esophageal AdenocarcinomaAGR2基因在Barrett"s食管中的差异表达及其肿瘤生物学功能和机制的研究
5.Differential Analysis of Gene Expression between U-251 Glioma Cells and Glioma Stem Cells;人胶质瘤细胞株U-251体外诱导肿瘤干细胞及其基因表达差异分析研究
6.The Research of SNPs on Igκ Gene Associated with Epithelial Cancer Susceptibility and the Heterogeneity of Ig Expressed in Cancer CellsIgκ基因SNP位点与肿瘤易感性以及肿瘤细胞表达Ig的异质性研究
7.Study of the Abnormal Transcriptional Expression of RASSF1A Gene in Lacrimal Gland Tumor and Its Clinical Significance;泪腺肿瘤RASSF1A基因表达异常及临床意义的研究
8.Gene Expression of Chemokines in Human Carcinoma Cell Lines with Different Metastatic Potential;不同转移潜能的肿瘤细胞中趋化因子差异表达的研究
9.Characterizations of Two Differentially Expressed Genes Related to Human Gliomas;人脑胶质瘤中二条差异表达基因的研究
10.All-trans Retinoic Acid Induced Differentially Genes Expression in Glioma cells全反式维甲酸诱导胶质瘤细胞基因的差异表达
11.Difference of Genes Expression in Pituitary of Tumour Mice with Sthenia Syndrome and Asthenia Syndrome荷瘤小鼠虚证、实证垂体基因表达的差异
12.Gene Expression Profile of Malignant Melanoma;应用基因芯片对皮肤恶性黑色素瘤差异表达基因的研究
13.Search of the Mutation of β-Catenin Gene and Its Products in Pancreatic Tumors;胰腺肿瘤β-连环蛋白基因变异及其产物表达状况的研究
14.A Study on the Expression of Tumor Specific Antigen MAGE, BAGE, GAGE in Ovarian Cancer Tissue and Ovarian Cancer Cell Lines;卵巢癌组织及细胞株中肿瘤特异性抗原MAGE、GAGE、BAGE基因表达的研究
15.Search of the Expression of p14～(ARF) and FHIT Protein in Thyroid Tumors;甲状腺肿瘤p14～（ARF）和FHIT基因的变异及其产物表达状况的研究
16.The Differential Expression of IL-2Rα in Malignant Tumors and Its Construction of Eukaryotic Expression Vector;IL-2Rα在不同肿瘤中的差异表达及其真核表达载体的构建
17.Expression of hk10 in Ovary Cancer Tissues卵巢浆液性肿瘤组织中hk10基因的表达
18.Experiment Studies on the Establishment of the Bear-tumor Mice Model and Gene Array Differential Expression between Local Tumor in Situ and Metastatic Tumor of Neuroblastoma;神经母细胞瘤细胞系原位荷瘤及转移瘤荷瘤鼠模型的建立及基因芯片差异表达的实验研究
相关短句/例句
differentially expressed genes差异表达基因
1.Analyses on thedifferentially expressed genes associated with murine double minute 2/p53 pathway in breast cancer;mdm2/p53通路相关的乳腺癌差异表达基因分析
2.Screening ofdifferentially expressed genes in rat brain repeatedly exposed to+Gz;正加速度重复暴露大鼠脑差异表达基因的筛选
3.Cloning and screening ofdifferentially expressed genes from the male gametophytes of Laminaria japonica Aresch;海带雄性配子体差异表达基因片段的克隆及筛选
3)differential gene expression差异基因表达
1.To elucidate thedifferential gene expression during the development of stamens in female flower buds of bitter melon gynoecious line induced with AgNO3, in the present study, it was studied at the levels of morphology and transcription genomics using morphologic observations, cDNA-AFLP, RT-PCR and reverse-Northern hybridization.为了研究AgNO3诱导下纯雌系苦瓜花蕾发育过程中的差异基因表达,本文运用形态学观察、cDNA-AFLP、RT-PCR和反向Northern杂交等技术在形态学和转录组学水平上对花蕾转雄进行了研究。
4)differentially expressed gene差异表达基因
1.Detection ofdifferentially expressed genes in human autosomal dominant polycystic kidney tissue;常染色体显性多囊肾组织差异表达基因的初步研究
2.Cloning ofdifferentially expressed genes of eosinophils from asthmatic patients by suppression subtractive hybridization;应用抑制消减杂交克隆支气管哮喘病人嗜酸细胞差异表达基因
3.Screening ofdifferentially expressed genes in the regeneration of injured spinal cord of neonatal rats;新生大鼠脊髓损伤修复差异表达基因的筛选
5)gene different expression基因差异表达
6)differential gen expression差异性基因表达
延伸阅读
表达谱差异分析表达谱差异分析(differential expression profiling)主要包括基因表达谱(gene expression profiling) 和蛋白质表达谱(protein expression profiling) 。大规模表达谱分析已经成为认识疾病分子机制的有利方法,在癌症研究等方面取得了一定的进展。成功的表达谱分析基于实验及其过程分析的有机结合。实验过程从关注的疾病开始,首先收集大量的疾病相关组织样本,样本数量可从10 多个到数百个,但必须足以对每一组织类型及个体差异进行比较分析,而且许多情况下不能仅简单地分为正常和疾病组织。例如,在对糖尿病的研究中,所收集的样本来自健康人、胰岛素耐受和糖尿病病人的不同试验阶段,如胰岛素治疗前后。样品还应包括其他器官的取材,以便进行基因表达的组织分布研究。为了便于对后来的实验数据进行分析管理,需采集并储存所有的组织样本和临床参数。接下来进行组织样本的处理,利用生物芯片(寡核苷酸芯片、cdna 芯片或全基因组芯片) 进行表达谱测定,并进行生物信息学分析。通常,表达谱的分析结果需进一步的实验加以证实。定量rt2pcr 是最灵敏的确证方法,该方法还可以将确证实验的范围扩大到原测组织以外的更广泛的组织和组织类型,揭示基因表达的组织分布情况。确证实验揭示了疾病相关基因。据此,可以进行进一步研究,探索这些基因的功能,开发新的治疗手段。例如,对于正常和疾病组织中表达有显著性变化的基因,可以进行新治疗靶点的鉴定和确定研究,或利用实验和分析工具研究分析其功能;对于疾病组织中活性升高的酶,可以当作前药活化酶进行鉴定研究。典型的表达谱能够显示疾病过程中有大量的已知基因表达的改变,而许多已知基因的代谢通路、表达产物酶学分类和蛋白质功能业已发表,将两者对照分析,可以鉴定出酶活性,选择其中可能成为前药活化酶的部分进行进一步研究;对于疾病特异的蛋白质,可以进行抗原表型分析,决定疫苗的开发策略。寻找差异表达基因的方法除芯片技术外,一些新的检测方法如差异显示pcr ( differential display pcr, dd－pcr) 、消减杂交( suppression subreactive hy bridization , ssh) 等也相继得到结合应用。
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